[It definitely shows that Tsuyu had to mature more quickly than some of the rest of their class, even those also with siblings, younger or older. Ochako actually quite appreciates her friend's level-headed, down to earth personality...it keeps her grounded, and balances out Ochako's rather energetic and youthful personality. She's not quite as genki-pilled as Hagakure or Mina, but she is pretty up there.]

Eeeh?! I never knew!! I must not have paid attention to the pictures in your room when we hang out or study... Will your siblings be okay now that you're living on campus? They weren't that much younger than you, were they?

[Ochako is assuming relatively young - possible primary school or so, maybe early middle school, but it must be tough now for her mother and father, if their eldest child was no longer available to babysit. Maybe they hired a sitter? Tsuyu wasn't crazy wealthy like Todoroki or Yaomomo, but she was decently well off, it seemed like.]